BDBM50087692 8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL354291

SMILES: O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCCCCCC1

InChI Key: InChIKey=GWNDTWSMNIBSRN-UHFFFAOYSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50087692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin/Orphanin FQ, NOP receptor (RAT)	BDBM50087692 (8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCCCCCC1 Show InChI InChI=1S/C23H35N3O/c27-22-23(26(19-24-22)21-13-9-6-10-14-21)15-17-25(18-16-23)20-11-7-4-2-1-3-5-8-12-20/h6,9-10,13-14,20H,1-5,7-8,11-12,15-19H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1				Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50087692 (8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCCCCCC1 Show InChI InChI=1S/C23H35N3O/c27-22-23(26(19-24-22)21-13-9-6-10-14-21)15-17-25(18-16-23)20-11-7-4-2-1-3-5-8-12-20/h6,9-10,13-14,20H,1-5,7-8,11-12,15-19H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the...				Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50087692 (8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCCCCCC1 Show InChI InChI=1S/C23H35N3O/c27-22-23(26(19-24-22)21-13-9-6-10-14-21)15-17-25(18-16-23)20-11-7-4-2-1-3-5-8-12-20/h6,9-10,13-14,20H,1-5,7-8,11-12,15-19H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the...				Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2
					More data for this Ligand-Target Pair
Opioid receptors; mu & delta (Rattus norvegicus (rat))	BDBM50087692 (8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCCCCCC1 Show InChI InChI=1S/C23H35N3O/c27-22-23(26(19-24-22)21-13-9-6-10-14-21)15-17-25(18-16-23)20-11-7-4-2-1-3-5-8-12-20/h6,9-10,13-14,20H,1-5,7-8,11-12,15-19H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition against binding of radioligand [Ile5,6-3H]-deltorphin to membrane from baby hamster kidney cells infected with forest virus encoding the ...				Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2
					More data for this Ligand-Target Pair
Nociceptin/mu opioid receptor (RAT)	BDBM50087692 (8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCCCCCC1 Show InChI InChI=1S/C23H35N3O/c27-22-23(26(19-24-22)21-13-9-6-10-14-21)15-17-25(18-16-23)20-11-7-4-2-1-3-5-8-12-20/h6,9-10,13-14,20H,1-5,7-8,11-12,15-19H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assay				Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2
					More data for this Ligand-Target Pair