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BDBM50087719 4-(5,7-Dichloro-2,3-dihydro-indol-1-yl)-1-(1-ethyl-propyl)-6-methyl-1H-[1,2,3]triazolo[4,5-c]pyridine::CHEMBL297868

SMILES: CCC(CC)n1nnc2c(nc(C)cc12)N1CCc2cc(Cl)cc(Cl)c12

InChI Key: InChIKey=BEGBSSPFQACGIG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087719   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))		BDBM50087719
PNG
(4-(5,7-Dichloro-2,3-dihydro-indol-1-yl)-1-(1-ethyl...)
Show SMILES CCC(CC)n1nnc2c(nc(C)cc12)N1CCc2cc(Cl)cc(Cl)c12
Show InChI InChI=1S/C19H21Cl2N5/c1-4-14(5-2)26-16-8-11(3)22-19(17(16)23-24-26)25-7-6-12-9-13(20)10-15(21)18(12)25/h8-10,14H,4-7H2,1-3H3
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 1.30n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.

J Med Chem 43: 1641-60 (2000)


BindingDB Entry DOI: 10.7270/Q29S1RRP
More data for this
Ligand-Target Pair