BDBM50088039 CHEMBL3427097

SMILES: CC1CCN(CC1)c1nc(ccc1CNC(=O)C(C1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F

InChI Key: InChIKey=GTVYDJJNJYGPKF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088039   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50088039 (CHEMBL3427097) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)C(C1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F Show InChI InChI=1S/C27H34F4N4O3S/c1-17-11-13-35(14-12-17)25-20(8-10-23(33-25)27(29,30)31)16-32-26(36)24(18-5-3-4-6-18)19-7-9-22(21(28)15-19)34-39(2,37)38/h7-10,15,17-18,24,34H,3-6,11-14,16H2,1-2H3,(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay				Bioorg Med Chem Lett 25: 2326-30 (2015) Article DOI: 10.1016/j.bmcl.2015.04.024 BindingDB Entry DOI: 10.7270/Q2Z60QSC
					More data for this Ligand-Target Pair