BDBM50088133 CHEMBL3427238

SMILES: COC(=O)CC(=O)NCCc1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1

InChI Key: InChIKey=XAFWLFYVMGYIOM-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50088133 (CHEMBL3427238) Show SMILES COC(=O)CC(=O)NCCc1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1 |r| Show InChI InChI=1S/C25H32N2O3/c1-19-4-3-16-27(19)17-14-21-7-11-23(12-8-21)22-9-5-20(6-10-22)13-15-26-24(28)18-25(29)30-2/h5-12,19H,3-4,13-18H2,1-2H3,(H,26,28)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Modulation of human histamine H3 receptor expressed in HEK293 cells assessed as change in forskolin-stimulated cAMP level after 1 hr by HTRF assay				ACS Med Chem Lett 6: 235-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00002 BindingDB Entry DOI: 10.7270/Q2PN97B5
					More data for this Ligand-Target Pair