BDBM50088136 CHEMBL3427235

SMILES: C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(CCNC(=O)C(C)(C)C(=O)OC(C)(C)C)cc1

InChI Key: InChIKey=CVVVHSAIWUMKNN-JOCHJYFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50088136 (CHEMBL3427235) Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(CCNC(=O)C(C)(C)C(=O)OC(C)(C)C)cc1 |r| Show InChI InChI=1S/C30H42N2O3/c1-22-8-7-20-32(22)21-18-24-11-15-26(16-12-24)25-13-9-23(10-14-25)17-19-31-27(33)30(5,6)28(34)35-29(2,3)4/h9-16,22H,7-8,17-21H2,1-6H3,(H,31,33)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
Temple University School of Pharmacy Curated by ChEMBL					Assay Description Modulation of human histamine H3 receptor expressed in HEK293 cells assessed as change in forskolin-stimulated cAMP level after 1 hr by HTRF assay				ACS Med Chem Lett 6: 235-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00002 BindingDB Entry DOI: 10.7270/Q2PN97B5
					More data for this Ligand-Target Pair