BDBM50088256 6,6'-dihydroxy-3,3,3',3'-tetramethyl-1,1'-spirobi[2,3-dihydro-1H-indene]-5,5'-dicarbaldehyde::CHEMBL417029

SMILES: CC1(C)CC2(CC(C)(C)c3cc(C=O)c(O)cc23)c2cc(O)c(C=O)cc12

InChI Key: InChIKey=ZLRCKGCSBDTDGQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50088256 (6,6'-dihydroxy-3,3,3',3'-tetramethyl-1,1'-spirobi[...) Show SMILES CC1(C)CC2(CC(C)(C)c3cc(C=O)c(O)cc23)c2cc(O)c(C=O)cc12 Show InChI InChI=1S/C23H24O4/c1-21(2)11-23(17-7-19(26)13(9-24)5-15(17)21)12-22(3,4)16-6-14(10-25)20(27)8-18(16)23/h5-10,26-27H,11-12H2,1-4H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of strand -transfer (ST) activity in the presence of Mn2+				J Med Chem 43: 2031-9 (2000) BindingDB Entry DOI: 10.7270/Q2B56J0B
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50088256 (6,6'-dihydroxy-3,3,3',3'-tetramethyl-1,1'-spirobi[...) Show SMILES CC1(C)CC2(CC(C)(C)c3cc(C=O)c(O)cc23)c2cc(O)c(C=O)cc12 Show InChI InChI=1S/C23H24O4/c1-21(2)11-23(17-7-19(26)13(9-24)5-15(17)21)12-22(3,4)16-6-14(10-25)20(27)8-18(16)23/h5-10,26-27H,11-12H2,1-4H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of 3'-processing (TC) in the presence of Mn2+ in vitro				J Med Chem 43: 2031-9 (2000) BindingDB Entry DOI: 10.7270/Q2B56J0B
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50088256 (6,6'-dihydroxy-3,3,3',3'-tetramethyl-1,1'-spirobi[...) Show SMILES CC1(C)CC2(CC(C)(C)c3cc(C=O)c(O)cc23)c2cc(O)c(C=O)cc12 Show InChI InChI=1S/C23H24O4/c1-21(2)11-23(17-7-19(26)13(9-24)5-15(17)21)12-22(3,4)16-6-14(10-25)20(27)8-18(16)23/h5-10,26-27H,11-12H2,1-4H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Tested in vitro against strand -transfer (ST) activity in the presence of Mg2+ as the cationic cofactor				J Med Chem 43: 2031-9 (2000) BindingDB Entry DOI: 10.7270/Q2B56J0B
					More data for this Ligand-Target Pair