BDBM50088343 CHEMBL3427781

SMILES: Clc1sc(cc1Br)S(=O)(=O)NCCc1c[nH]c2ccccc12

InChI Key: InChIKey=GFFPHNCWJPRDOK-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088343   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM50088343 (CHEMBL3427781) Show SMILES Clc1sc(cc1Br)S(=O)(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C14H12BrClN2O2S2/c15-11-7-13(21-14(11)16)22(19,20)18-6-5-9-8-17-12-4-2-1-3-10(9)12/h1-4,7-8,17-18H,5-6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
Astex Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to of humanised RAD51 C-terminal ATPase domain (with deletion of L2 loop residues 288 to 314) from Pyrococcus furiosus expressed in ...				J Med Chem 60: 89-99 (2017) Article DOI: 10.1021/acs.jmedchem.6b01123 BindingDB Entry DOI: 10.7270/Q2R78H5B
					More data for this Ligand-Target Pair
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM50088343 (CHEMBL3427781) Show SMILES Clc1sc(cc1Br)S(=O)(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C14H12BrClN2O2S2/c15-11-7-13(21-14(11)16)22(19,20)18-6-5-9-8-17-12-4-2-1-3-10(9)12/h1-4,7-8,17-18H,5-6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to RAD51 (unknown origin) by isothermal calorimetry				Bioorg Med Chem Lett 25: 2461-8 (2015) Article DOI: 10.1016/j.bmcl.2015.04.089 BindingDB Entry DOI: 10.7270/Q2SF2XVC
					More data for this Ligand-Target Pair