BDBM50088460 1-(2-Chloro-phenyl)-3-(2-phenyl-quinazolin-4-yl)-urea::CHEMBL70955

SMILES: Clc1ccccc1NC(=O)Nc1nc(nc2ccccc12)-c1ccccc1

InChI Key: InChIKey=FVIHUPFBXYUTNY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50088460 (1-(2-Chloro-phenyl)-3-(2-phenyl-quinazolin-4-yl)-u...) Show SMILES Clc1ccccc1NC(=O)Nc1nc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C21H15ClN4O/c22-16-11-5-7-13-18(16)24-21(27)26-20-15-10-4-6-12-17(15)23-19(25-20)14-8-2-1-3-9-14/h1-13H,(H2,23,24,25,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cells				J Med Chem 43: 2227-38 (2000) BindingDB Entry DOI: 10.7270/Q2T72GNJ
					More data for this Ligand-Target Pair