BDBM50088477 1-(2-Phenyl-quinazolin-4-yl)-3-o-tolyl-urea::CHEMBL71756

SMILES: Cc1ccccc1NC(=O)Nc1nc(nc2ccccc12)-c1ccccc1

InChI Key: InChIKey=NCIFTLPMKFHFIK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50088477 (1-(2-Phenyl-quinazolin-4-yl)-3-o-tolyl-urea | CHEM...) Show SMILES Cc1ccccc1NC(=O)Nc1nc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C22H18N4O/c1-15-9-5-7-13-18(15)24-22(27)26-21-17-12-6-8-14-19(17)23-20(25-21)16-10-3-2-4-11-16/h2-14H,1H3,(H2,23,24,25,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.15E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cells				J Med Chem 43: 2227-38 (2000) BindingDB Entry DOI: 10.7270/Q2T72GNJ
					More data for this Ligand-Target Pair