BDBM50088497 CHEMBL3526543

SMILES: C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(cc4c3F)C(O)=O)c2c1C

InChI Key: InChIKey=JEFQSGODDXULMW-SECBINFHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50088497 (CHEMBL3526543) Show SMILES C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(cc4c3F)C(O)=O)c2c1C |r| Show InChI InChI=1S/C19H17FN4O5/c1-9(25)7-28-15-6-24-17(10(15)2)18(21-8-22-24)29-14-4-3-12-11(16(14)20)5-13(23-12)19(26)27/h3-6,8-9,23,25H,7H2,1-2H3,(H,26,27)/t9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant FGFR-1				Drug Metab Dispos 39: 891-903 (2011) Article DOI: 10.1124/dmd.110.037341 BindingDB Entry DOI: 10.7270/Q2F191FN
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50088497 (CHEMBL3526543) Show SMILES C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(cc4c3F)C(O)=O)c2c1C |r| Show InChI InChI=1S/C19H17FN4O5/c1-9(25)7-28-15-6-24-17(10(15)2)18(21-8-22-24)29-14-4-3-12-11(16(14)20)5-13(23-12)19(26)27/h3-6,8-9,23,25H,7H2,1-2H3,(H,26,27)/t9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR-2				Drug Metab Dispos 39: 891-903 (2011) Article DOI: 10.1124/dmd.110.037341 BindingDB Entry DOI: 10.7270/Q2F191FN
					More data for this Ligand-Target Pair