BDBM50088507 CHEBI:63804::CHEMBL1908021

SMILES: Oc1ccc(cc1)C1(NC(=O)NC1=O)c1ccccc1

InChI Key: InChIKey=XEEDURHPFVXALT-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50088507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine-5'-diphosphoglucuronosyltransferase 1A1 (Homo sapiens (Human))	BDBM50088507 (CHEBI:63804 | CHEMBL1908021) Show SMILES Oc1ccc(cc1)C1(NC(=O)NC1=O)c1ccccc1 Show InChI InChI=1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS method				Drug Metab Dispos 39: 322-9 (2011) Article DOI: 10.1124/dmd.110.035030 BindingDB Entry DOI: 10.7270/Q2PC343R
					More data for this Ligand-Target Pair
Uridine-5'-diphosphoglucuronosyltransferase 1A1 (Homo sapiens (Human))	BDBM50088507 (CHEBI:63804 | CHEMBL1908021) Show SMILES Oc1ccc(cc1)C1(NC(=O)NC1=O)c1ccccc1 Show InChI InChI=1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS method				Drug Metab Dispos 39: 322-9 (2011) Article DOI: 10.1124/dmd.110.035030 BindingDB Entry DOI: 10.7270/Q2PC343R
					More data for this Ligand-Target Pair
Aldose reductase (Homo sapiens (Human))	BDBM50088507 (CHEBI:63804 | CHEMBL1908021) Show SMILES Oc1ccc(cc1)C1(NC(=O)NC1=O)c1ccccc1 Show InChI InChI=1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of human Protein kinase C delta				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Aldose reductase (Homo sapiens (Human))	BDBM50088507 (CHEBI:63804 | CHEMBL1908021) Show SMILES Oc1ccc(cc1)C1(NC(=O)NC1=O)c1ccccc1 Show InChI InChI=1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of protein kinase C epsilon expressed in Sf-9 cells				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Aldose reductase (Homo sapiens (Human))	BDBM50088507 (CHEBI:63804 | CHEMBL1908021) Show SMILES Oc1ccc(cc1)C1(NC(=O)NC1=O)c1ccccc1 Show InChI InChI=1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of human Protein kinase C beta 1				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Aldose reductase (Homo sapiens (Human))	BDBM50088507 (CHEBI:63804 | CHEMBL1908021) Show SMILES Oc1ccc(cc1)C1(NC(=O)NC1=O)c1ccccc1 Show InChI InChI=1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of protein kinase C epsilon expressed in Sf-9 cells				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair