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BDBM50088523 CHEMBL3527383

SMILES: [H][C@@]1([C@H](OC)[C@@H](CC[C@]11CO1)OC(=O)N[C@H](C(C)C)C(N)=O)[C@@]1(C)O[C@@H]1C\C=C(/C)CO

InChI Key: InChIKey=XVDQGGLGAFFNJF-IRALCKFWSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088523   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microtubule-associated protein 2


(Homo sapiens (Human))		BDBM50088523
PNG
(CHEMBL3527383)
Show SMILES [H][C@@]1([C@H](OC)[C@@H](CC[C@]11CO1)OC(=O)N[C@H](C(C)C)C(N)=O)[C@@]1(C)O[C@@H]1C\C=C(/C)CO |r|
Show InChI InChI=1S/C22H36N2O7/c1-12(2)16(19(23)26)24-20(27)30-14-8-9-22(11-29-22)18(17(14)28-5)21(4)15(31-21)7-6-13(3)10-25/h6,12,14-18,25H,7-11H2,1-5H3,(H2,23,26)(H,24,27)/b13-6+/t14-,15-,16-,17-,18-,21+,22+/m1/s1
KEGG

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PC cid
PC sid
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Similars
Article
PubMed
n/an/an/an/a 7.10n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of MetAP2 activity in HUVEC assessed as inhibition of cell proliferation by MTT assay

Drug Metab Dispos 41: 814-26 (2013)


Article DOI: 10.1124/dmd.112.048355
BindingDB Entry DOI: 10.7270/Q2NC62XH
More data for this
Ligand-Target Pair