BDBM50088542 CHEMBL3576950

SMILES: NC(=O)c1cccc(n1)-c1ccc2N(CCOCc2c1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=HMXYTGIRFTYLJV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088542   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50088542 (CHEMBL3576950) Show SMILES NC(=O)c1cccc(n1)-c1ccc2N(CCOCc2c1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H18F3N3O2/c23-22(24,25)16-5-7-17(8-6-16)28-10-11-30-13-15-12-14(4-9-20(15)28)18-2-1-3-19(27-18)21(26)29/h1-9,12H,10-11,13H2,(H2,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay				Bioorg Med Chem Lett 25: 48-52 (2014) Article DOI: 10.1016/j.bmcl.2014.11.023 BindingDB Entry DOI: 10.7270/Q2862J67
					More data for this Ligand-Target Pair