BDBM50088569 2-(5-Benzoyl-2-methoxy-phenyl)-propionic acid::CHEMBL74276
SMILES: COc1ccc(cc1C(C)C(O)=O)C(=O)c1ccccc1
InChI Key: InChIKey=PVGMTSZPGWKSKV-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclooxygenase (Homo sapiens (Human)) | BDBM50088569 (2-(5-Benzoyl-2-methoxy-phenyl)-propionic acid | CH...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratorios Menarini Curated by ChEMBL | Assay Description Concentration required for 50% inhibition against Prostaglandin G/H synthase 2 from human | J Med Chem 43: 2280-4 (2000) BindingDB Entry DOI: 10.7270/Q2PG1QZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human)) | BDBM50088569 (2-(5-Benzoyl-2-methoxy-phenyl)-propionic acid | CH...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratorios Menarini Curated by ChEMBL | Assay Description Concentration required for 50% inhibition against Prostaglandin G/H synthase 1 from human | J Med Chem 43: 2280-4 (2000) BindingDB Entry DOI: 10.7270/Q2PG1QZ8 | |||||||||||
More data for this Ligand-Target Pair |