BDBM50088643 2-Chloro-5-((R)-pyrrolidin-3-yloxy)-[3,4']bipyridinyl::CHEMBL273709

SMILES: Clc1ncc(O[C@@H]2CCNC2)cc1-c1ccncc1

InChI Key: InChIKey=XVYPXIBYGFWIKK-LLVKDONJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088643   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50088643 (2-Chloro-5-((R)-pyrrolidin-3-yloxy)-[3,4']bipyridi...) Show SMILES Clc1ncc(O[C@@H]2CCNC2)cc1-c1ccncc1 Show InChI InChI=1S/C14H14ClN3O/c15-14-13(10-1-4-16-5-2-10)7-12(9-18-14)19-11-3-6-17-8-11/h1-2,4-5,7,9,11,17H,3,6,8H2/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Evaluated for binding affinity towards nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 10: 1063-6 (2000) BindingDB Entry DOI: 10.7270/Q2PK0HBC
					More data for this Ligand-Target Pair