BDBM50088651 4-[2-Chloro-5-((R)-pyrrolidin-3-yloxy)-pyridin-3-yl]-benzonitrile::CHEMBL268015

SMILES: Clc1ncc(O[C@@H]2CCNC2)cc1-c1ccc(cc1)C#N

InChI Key: InChIKey=QEHPFSYDPGOMJI-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50088651 (4-[2-Chloro-5-((R)-pyrrolidin-3-yloxy)-pyridin-3-y...) Show SMILES Clc1ncc(O[C@@H]2CCNC2)cc1-c1ccc(cc1)C#N Show InChI InChI=1S/C16H14ClN3O/c17-16-15(12-3-1-11(8-18)2-4-12)7-14(10-20-16)21-13-5-6-19-9-13/h1-4,7,10,13,19H,5-6,9H2/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Evaluated for binding affinity towards nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 10: 1063-6 (2000) BindingDB Entry DOI: 10.7270/Q2PK0HBC
					More data for this Ligand-Target Pair