BDBM50088654 CHEMBL273861::N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methyl-2,8-dioxo-2,3,4,8-tetrahydro-1H-[1,7]naphthyridin-7-yl)-acetamide

SMILES: Cc1cc2CCC(=O)Nc2c(=O)n1CC(=O)NCc1ccc(N)nc1C

InChI Key: InChIKey=GZLSRIOJUOYOBV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50088654 (CHEMBL273861 | N-(6-Amino-2-methyl-pyridin-3-ylmet...) Show SMILES Cc1cc2CCC(=O)Nc2c(=O)n1CC(=O)NCc1ccc(N)nc1C Show InChI InChI=1S/C18H21N5O3/c1-10-7-12-4-6-15(24)22-17(12)18(26)23(10)9-16(25)20-8-13-3-5-14(19)21-11(13)2/h3,5,7H,4,6,8-9H2,1-2H3,(H2,19,21)(H,20,25)(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description The compound was tested for its ability to inhibit thrombin.				Bioorg Med Chem Lett 10: 1069-72 (2000) BindingDB Entry DOI: 10.7270/Q2DZ07J2
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50088654 (CHEMBL273861 | N-(6-Amino-2-methyl-pyridin-3-ylmet...) Show SMILES Cc1cc2CCC(=O)Nc2c(=O)n1CC(=O)NCc1ccc(N)nc1C Show InChI InChI=1S/C18H21N5O3/c1-10-7-12-4-6-15(24)22-17(12)18(26)23(10)9-16(25)20-8-13-3-5-14(19)21-11(13)2/h3,5,7H,4,6,8-9H2,1-2H3,(H2,19,21)(H,20,25)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description The compound was tested for its ability to inhibit trypsin.				Bioorg Med Chem Lett 10: 1069-72 (2000) BindingDB Entry DOI: 10.7270/Q2DZ07J2
					More data for this Ligand-Target Pair