BDBM50088695 2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propylsulfanyl}-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-ylamine::CHEMBL11936
SMILES: COc1ccccc1N1CCN(CCCSc2nc(N)c3c(C)c(C)sc3n2)CC1
InChI Key: InChIKey=PVXJBAIAVSZADW-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088695 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Catania Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus membranes | Bioorg Med Chem Lett 10: 1089-92 (2000) BindingDB Entry DOI: 10.7270/Q25D8R2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50088695 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Catania Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of rat cortex membranes | Bioorg Med Chem Lett 10: 1089-92 (2000) BindingDB Entry DOI: 10.7270/Q25D8R2B | |||||||||||
More data for this Ligand-Target Pair |