BDBM50088942 7-{2-Butyl-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]-benzoimidazol-1-ylmethyl}-naphthalene-2-carboxamidine::CHEMBL177225

SMILES: CCCCc1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N

InChI Key: InChIKey=KFGFAIRWDMAAQY-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088942   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50088942 (7-{2-Butyl-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]...) Show SMILES CCCCc1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N Show InChI InChI=1S/C30H36N6O/c1-3-4-5-29-34-27-11-10-26(37-25-12-14-35(15-13-25)20(2)31)18-28(27)36(29)19-21-6-7-22-8-9-23(30(32)33)17-24(22)16-21/h6-11,16-18,25,31H,3-5,12-15,19H2,1-2H3,(H3,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Coagulation factor X				Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N
					More data for this Ligand-Target Pair
Trypsin (Bos taurus (bovine))	BDBM50088942 (7-{2-Butyl-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]...) Show SMILES CCCCc1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N Show InChI InChI=1S/C30H36N6O/c1-3-4-5-29-34-27-11-10-26(37-25-12-14-35(15-13-25)20(2)31)18-28(27)36(29)19-21-6-7-22-8-9-23(30(32)33)17-24(22)16-21/h6-11,16-18,25,31H,3-5,12-15,19H2,1-2H3,(H3,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against bovine cationic trypsin				Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50088942 (7-{2-Butyl-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]...) Show SMILES CCCCc1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N Show InChI InChI=1S/C30H36N6O/c1-3-4-5-29-34-27-11-10-26(37-25-12-14-35(15-13-25)20(2)31)18-28(27)36(29)19-21-6-7-22-8-9-23(30(32)33)17-24(22)16-21/h6-11,16-18,25,31H,3-5,12-15,19H2,1-2H3,(H3,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against human coagulation factor II				Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N
					More data for this Ligand-Target Pair