BDBM50088951 7-{2-Ethyl-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]-benzoimidazol-1-ylmethyl}-naphthalene-2-carboxamidine::CHEMBL367840

SMILES: CCc1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N

InChI Key: InChIKey=RFEXMZCPQGEUSL-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50088951 (7-{2-Ethyl-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]...) Show SMILES CCc1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N Show InChI InChI=1S/C28H32N6O/c1-3-27-32-25-9-8-24(35-23-10-12-33(13-11-23)18(2)29)16-26(25)34(27)17-19-4-5-20-6-7-21(28(30)31)15-22(20)14-19/h4-9,14-16,23,29H,3,10-13,17H2,1-2H3,(H3,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Coagulation factor X				Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N
					More data for this Ligand-Target Pair
Trypsin (Bos taurus (bovine))	BDBM50088951 (7-{2-Ethyl-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]...) Show SMILES CCc1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N Show InChI InChI=1S/C28H32N6O/c1-3-27-32-25-9-8-24(35-23-10-12-33(13-11-23)18(2)29)16-26(25)34(27)17-19-4-5-20-6-7-21(28(30)31)15-22(20)14-19/h4-9,14-16,23,29H,3,10-13,17H2,1-2H3,(H3,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against bovine cationic trypsin				Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50088951 (7-{2-Ethyl-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]...) Show SMILES CCc1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N Show InChI InChI=1S/C28H32N6O/c1-3-27-32-25-9-8-24(35-23-10-12-33(13-11-23)18(2)29)16-26(25)34(27)17-19-4-5-20-6-7-21(28(30)31)15-22(20)14-19/h4-9,14-16,23,29H,3,10-13,17H2,1-2H3,(H3,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against human coagulation factor II				Bioorg Med Chem Lett 10: 963-6 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6X0N
					More data for this Ligand-Target Pair