BDBM50089076 CHEMBL3577642

SMILES: COc1ccc(NC(=O)COc2ccc(\C=C3/N=C(N(C3=O)c3ccc(OC)cc3)c3ccccc3)cc2)cc1

InChI Key: InChIKey=OJSJZUVJRVIKSH-BRPDVVIDSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50089076 (CHEMBL3577642) Show SMILES COc1ccc(NC(=O)COc2ccc(\C=C3/N=C(N(C3=O)c3ccc(OC)cc3)c3ccccc3)cc2)cc1 |c:17| Show InChI InChI=1S/C32H27N3O5/c1-38-26-16-10-24(11-17-26)33-30(36)21-40-28-14-8-22(9-15-28)20-29-32(37)35(25-12-18-27(39-2)19-13-25)31(34-29)23-6-4-3-5-7-23/h3-20H,21H2,1-2H3,(H,33,36)/b29-20-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	345	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of p38alpha MAP kinase (unknown origin) using GFP-ATF2 as substrate after 1 hr by TR-FRET assay				Eur J Med Chem 94: 397-404 (2015) Article DOI: 10.1016/j.ejmech.2015.03.008 BindingDB Entry DOI: 10.7270/Q2BZ67SV
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM50089076 (CHEMBL3577642) Show SMILES COc1ccc(NC(=O)COc2ccc(\C=C3/N=C(N(C3=O)c3ccc(OC)cc3)c3ccccc3)cc2)cc1 |c:17| Show InChI InChI=1S/C32H27N3O5/c1-38-26-16-10-24(11-17-26)33-30(36)21-40-28-14-8-22(9-15-28)20-29-32(37)35(25-12-18-27(39-2)19-13-25)31(34-29)23-6-4-3-5-7-23/h3-20H,21H2,1-2H3,(H,33,36)/b29-20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of ERK1 (unknown origin) using GFP-ATF2 as substrate after 1 hr by TR-FRET assay				Eur J Med Chem 94: 397-404 (2015) Article DOI: 10.1016/j.ejmech.2015.03.008 BindingDB Entry DOI: 10.7270/Q2BZ67SV
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50089076 (CHEMBL3577642) Show SMILES COc1ccc(NC(=O)COc2ccc(\C=C3/N=C(N(C3=O)c3ccc(OC)cc3)c3ccccc3)cc2)cc1 |c:17| Show InChI InChI=1S/C32H27N3O5/c1-38-26-16-10-24(11-17-26)33-30(36)21-40-28-14-8-22(9-15-28)20-29-32(37)35(25-12-18-27(39-2)19-13-25)31(34-29)23-6-4-3-5-7-23/h3-20H,21H2,1-2H3,(H,33,36)/b29-20-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin) using GFP-ATF2 as substrate after 1 hr by TR-FRET assay				Eur J Med Chem 94: 397-404 (2015) Article DOI: 10.1016/j.ejmech.2015.03.008 BindingDB Entry DOI: 10.7270/Q2BZ67SV
					More data for this Ligand-Target Pair