BDBM50089107 CHEMBL3577726

SMILES: CCN(CC)c1cccc(c1)C#Cc1cc(O[C@@H](C)COC)cc(c1)C(=O)Nc1ccn(C)n1

InChI Key: InChIKey=PJSFOJZUAHBGIV-FQEVSTJZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50089107 (CHEMBL3577726) Show SMILES CCN(CC)c1cccc(c1)C#Cc1cc(O[C@@H](C)COC)cc(c1)C(=O)Nc1ccn(C)n1 |r| Show InChI InChI=1S/C27H32N4O3/c1-6-31(7-2)24-10-8-9-21(16-24)11-12-22-15-23(18-25(17-22)34-20(3)19-33-5)27(32)28-26-13-14-30(4)29-26/h8-10,13-18,20H,6-7,19H2,1-5H3,(H,28,29,32)/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	163	n/a	n/a	n/a	n/a
Yuhan Research Institute Curated by ChEMBL					Assay Description Activation of recombinant human pancreatic glucokinase using 10 mM glucose as substrate by G6PDH coupled assay				ACS Med Chem Lett 6: 296-301 (2015) Article DOI: 10.1021/ml5004712 BindingDB Entry DOI: 10.7270/Q2ZP47VT
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