BDBM50089371 CHEMBL3577957

SMILES: Cl.O=C(N1CCN(CC1)C1CC1)c1ccc(CN2CCOCC2)cc1

InChI Key: InChIKey=MRTJHEDYFUFHHQ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50089371 (CHEMBL3577957) Show SMILES Cl.O=C(N1CCN(CC1)C1CC1)c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C19H27N3O2.ClH/c23-19(22-9-7-21(8-10-22)18-5-6-18)17-3-1-16(2-4-17)15-20-11-13-24-14-12-20;/h1-4,18H,5-15H2;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Company Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 mins				ACS Med Chem Lett 6: 450-4 (2015) Article DOI: 10.1021/ml5005156 BindingDB Entry DOI: 10.7270/Q22F7Q59
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50089371 (CHEMBL3577957) Show SMILES Cl.O=C(N1CCN(CC1)C1CC1)c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C19H27N3O2.ClH/c23-19(22-9-7-21(8-10-22)18-5-6-18)17-3-1-16(2-4-17)15-20-11-13-24-14-12-20;/h1-4,18H,5-15H2;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Company Curated by ChEMBL					Assay Description Displacement of [3H]-astemizole from human ERG expressed in HEK293 cells after 60 mins by scintillation counting analysis				ACS Med Chem Lett 6: 450-4 (2015) Article DOI: 10.1021/ml5005156 BindingDB Entry DOI: 10.7270/Q22F7Q59
					More data for this Ligand-Target Pair