BDBM50089383 CHEMBL1707983

SMILES: CN1CCN(CC1)C(=O)c1ccc(CN2CCOCC2)cc1

InChI Key: InChIKey=LWBZVRUFDRCWEP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50089383 (CHEMBL1707983) Show SMILES CN1CCN(CC1)C(=O)c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C17H25N3O2/c1-18-6-8-20(9-7-18)17(21)16-4-2-15(3-5-16)14-19-10-12-22-13-11-19/h2-5H,6-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Company Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 mins				ACS Med Chem Lett 6: 450-4 (2015) Article DOI: 10.1021/ml5005156 BindingDB Entry DOI: 10.7270/Q22F7Q59
					More data for this Ligand-Target Pair