BDBM50089580 CHEMBL3578209

SMILES: CSc1nc(NCCc2cccc(Cl)c2)c2cnn(\C=C\c3ccccc3)c2n1

InChI Key: InChIKey=UEZMCOBJEQJJJY-ACCUITESSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50089580 (CHEMBL3578209) Show SMILES CSc1nc(NCCc2cccc(Cl)c2)c2cnn(\C=C\c3ccccc3)c2n1 Show InChI InChI=1S/C22H20ClN5S/c1-29-22-26-20(24-12-10-17-8-5-9-18(23)14-17)19-15-25-28(21(19)27-22)13-11-16-6-3-2-4-7-16/h2-9,11,13-15H,10,12H2,1H3,(H,24,26,27)/b13-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...				J Med Chem 58: 4590-609 (2015) Article DOI: 10.1021/acs.jmedchem.5b00140 BindingDB Entry DOI: 10.7270/Q29025HZ
					More data for this Ligand-Target Pair