BindingDB PrimarySearch

null

SMILES: CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O

InChI Key: InChIKey=PAONCRJPUQXPRW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50089910
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UPR Centre Curated by PDSP K_i Database									Mol Pharmacol 50: 923-30 (1996) BindingDB Entry DOI: 10.7270/Q2M61HS5
UPR Centre Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UPR Centre Curated by PDSP K_i Database									Mol Pharmacol 50: 923-30 (1996) BindingDB Entry DOI: 10.7270/Q2M61HS5
UPR Centre Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist potency against cloned Metabotropic glutamate receptor 2				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 3 (RAT)	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 298: 453-60 (2001) Article DOI: 10.1016/j.bioorg.2016.02.004 BindingDB Entry DOI: 10.7270/Q2V986M2
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Neuropharmacology 40: 170-7 (2001) Article DOI: 10.1016/s0028-3908(00)00128-3 BindingDB Entry DOI: 10.7270/Q27P8WZ1
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	4.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6).				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned human metabotropic glutamate receptor 1				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned metabotropic glutamate receptor 5				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50089910 (2-Amino-2-(4-phosphono-phenyl)-propionic acid \| 2-...) Show SMILES CC(N)(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP K_i Database									J Neurochem 71: 2558-64 (1998) Article DOI: 10.1046/j.1471-4159.1998.71062558.x BindingDB Entry DOI: 10.7270/Q25D8QCZ
F. Hoffmann-La Roche Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair