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BDBM50089984 4'-(3-Butyl-1,4-dioxo-2,3-diaza-spiro[4.4]non-2-ylmethyl)-biphenyl-2-sulfonic acid benzoylamide::CHEMBL91113

SMILES: CCCCN1N(Cc2ccc(cc2)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)C(=O)C2(CCCC2)C1=O

InChI Key: InChIKey=IJQYBWYBOYYDFK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089984   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))		BDBM50089984
PNG
(4'-(3-Butyl-1,4-dioxo-2,3-diaza-spiro[4.4]non-2-yl...)
Show SMILES CCCCN1N(Cc2ccc(cc2)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)C(=O)C2(CCCC2)C1=O
Show InChI InChI=1S/C31H33N3O5S/c1-2-3-21-33-29(36)31(19-9-10-20-31)30(37)34(33)22-23-15-17-24(18-16-23)26-13-7-8-14-27(26)40(38,39)32-28(35)25-11-5-4-6-12-25/h4-8,11-18H,2-3,9-10,19-22H2,1H3,(H,32,35)
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PubMed
 10n/an/an/an/an/an/an/an/a



Université de Lille 2

Curated by ChEMBL


Assay Description
Binding affinity against AT1 in human hepatoma cell line, PLC-PRF-5

J Med Chem 43: 2685-97 (2000)


BindingDB Entry DOI: 10.7270/Q22B8X8G
More data for this
Ligand-Target Pair