BDBM50090283 2-Diphenylacetylamino-5-guanidino-pentanoic acid ((S)-1-phenyl-ethyl)-amide::CHEMBL433627
SMILES: C[C@H](NC(=O)C(CCCNC(N)=N)NC(=O)C(c1ccccc1)c1ccccc1)c1ccccc1
InChI Key: InChIKey=JWTLMJAUZBYAPO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuropeptide Y receptor type 1 (Homo sapiens (Human)) | BDBM50090283 (2-Diphenylacetylamino-5-guanidino-pentanoic acid (...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Regensburg Curated by ChEMBL | Assay Description NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine NPY (10 nM) stimulated increase in the intracellular [Ca2+] concentr... | Bioorg Med Chem Lett 10: 1597-600 (2000) BindingDB Entry DOI: 10.7270/Q2HD7TWN | |||||||||||
More data for this Ligand-Target Pair |