BDBM50090372 3-(4-Methoxy-benzenesulfonyl)-4-phenyl-pentanoic acid hydroxyamide::CHEMBL43667
SMILES: COc1ccc(cc1)S(=O)(=O)C(CC(=O)NO)C(C)c1ccccc1
InChI Key: InChIKey=MTRUAHVPTPWCQA-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50090372 (3-(4-Methoxy-benzenesulfonyl)-4-phenyl-pentanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rhone Poulenc Rorer Curated by ChEMBL | Assay Description In vitro inhibition of human recombinant Matrix metalloproteinase-2. | Bioorg Med Chem Lett 10: 1637-40 (2000) BindingDB Entry DOI: 10.7270/Q20G3JDK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50090372 (3-(4-Methoxy-benzenesulfonyl)-4-phenyl-pentanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rhone Poulenc Rorer Curated by ChEMBL | Assay Description In vitro inhibition of human recombinant Matrix metalloproteinase-3. | Bioorg Med Chem Lett 10: 1637-40 (2000) BindingDB Entry DOI: 10.7270/Q20G3JDK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interstitial collagenase (Homo sapiens (Human)) | BDBM50090372 (3-(4-Methoxy-benzenesulfonyl)-4-phenyl-pentanoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rhone Poulenc Rorer Curated by ChEMBL | Assay Description In vitro inhibition of human recombinant Matrix metalloproteinase-1. | Bioorg Med Chem Lett 10: 1637-40 (2000) BindingDB Entry DOI: 10.7270/Q20G3JDK | |||||||||||
More data for this Ligand-Target Pair |