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SMILES: CC\C(=C(\c1ccc(\C=C\C(O)=O)cc1)c1ccc2[nH]cnc2c1)c1ccccc1

InChI Key: InChIKey=CDDSPKOUQMXBPV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090469   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))		BDBM50090469
PNG
(CHEMBL3581639)
Show SMILES CC\C(=C(\c1ccc(\C=C\C(O)=O)cc1)c1ccc2[nH]cnc2c1)c1ccccc1
Show InChI InChI=1S/C23H21NO5/c1-13-4-6-16(7-5-13)19-12-18(8-9-20(19)25)29-21-14(2)10-17(11-15(21)3)24-22(26)23(27)28/h4-12,25H,1-3H3,(H,24,26)(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 957n/an/an/an/a



Seragon Pharmaceuticals

Curated by ChEMBL


Assay Description
Induction of estrogen receptor-alpha degradation in human MCF7 cells after 4 hrs by in-cell western assay

J Med Chem 58: 4888-904 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00054
BindingDB Entry DOI: 10.7270/Q29W0H7Q
More data for this
Ligand-Target Pair