BDBM50090497 (S)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-6-one O-methyl-oxime::CHEMBL47188

SMILES: CO\N=C1/CN2CC1[C@H](CC2)c1ccc(Cl)cc1

InChI Key: InChIKey=UXYPLFVCIANMBF-CMWRLFAESA-N

Data: 8 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50090497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50090497 ((S)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES CO\N=C1/CN2CC1[C@H](CC2)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN2O/c1-18-16-14-9-17-7-6-12(13(14)8-17)10-2-4-11(15)5-3-10/h2-5,12-13H,6-9H2,1H3/b16-14+/t12-,13?/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	305	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE binding to norepinephrine transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50090497 ((S)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES CO\N=C1/CN2CC1[C@H](CC2)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN2O/c1-18-16-14-9-17-7-6-12(13(14)8-17)10-2-4-11(15)5-3-10/h2-5,12-13H,6-9H2,1H3/b16-14+/t12-,13?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	503	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus)	BDBM50090497 ((S)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES CO\N=C1/CN2CC1[C@H](CC2)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN2O/c1-18-16-14-9-17-7-6-12(13(14)8-17)10-2-4-11(15)5-3-10/h2-5,12-13H,6-9H2,1H3/b16-14+/t12-,13?/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	871	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50090497 ((S)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES CO\N=C1/CN2CC1[C@H](CC2)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN2O/c1-18-16-14-9-17-7-6-12(13(14)8-17)10-2-4-11(15)5-3-10/h2-5,12-13H,6-9H2,1H3/b16-14+/t12-,13?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50090497 ((S)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES CO\N=C1/CN2CC1[C@H](CC2)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN2O/c1-18-16-14-9-17-7-6-12(13(14)8-17)10-2-4-11(15)5-3-10/h2-5,12-13H,6-9H2,1H3/b16-14+/t12-,13?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50090497 ((S)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES CO\N=C1/CN2CC1[C@H](CC2)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN2O/c1-18-16-14-9-17-7-6-12(13(14)8-17)10-2-4-11(15)5-3-10/h2-5,12-13H,6-9H2,1H3/b16-14+/t12-,13?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50090497 ((S)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES CO\N=C1/CN2CC1[C@H](CC2)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN2O/c1-18-16-14-9-17-7-6-12(13(14)8-17)10-2-4-11(15)5-3-10/h2-5,12-13H,6-9H2,1H3/b16-14+/t12-,13?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50090497 ((S)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES CO\N=C1/CN2CC1[C@H](CC2)c1ccc(Cl)cc1 Show InChI InChI=1S/C14H17ClN2O/c1-18-16-14-9-17-7-6-12(13(14)8-17)10-2-4-11(15)5-3-10/h2-5,12-13H,6-9H2,1H3/b16-14+/t12-,13?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair