BDBM50090630 1-(3-Chloro-phenyl)-4-(4-methanesulfonyl-phenyl)-3-phenyl-1,5-dihydro-pyrrol-2-one::CHEMBL49114

SMILES: CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)N(C1)c1cccc(Cl)c1)c1ccccc1

InChI Key: InChIKey=LVOBPVDFMBILJC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50090630 (1-(3-Chloro-phenyl)-4-(4-methanesulfonyl-phenyl)-3...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)N(C1)c1cccc(Cl)c1)c1ccccc1 |t:11| Show InChI InChI=1S/C23H18ClNO3S/c1-29(27,28)20-12-10-16(11-13-20)21-15-25(19-9-5-8-18(24)14-19)23(26)22(21)17-6-3-2-4-7-17/h2-14H,15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Barcelona Curated by ChEMBL					Assay Description Biochemical index for Prostaglandin G/H synthase 2 measured as, PGE-2 levels in lipopolysaccharide (LPS)-challenged human whole blood				Bioorg Med Chem Lett 10: 1745-8 (2000) BindingDB Entry DOI: 10.7270/Q2ZG6RH7
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50090630 (1-(3-Chloro-phenyl)-4-(4-methanesulfonyl-phenyl)-3...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)N(C1)c1cccc(Cl)c1)c1ccccc1 |t:11| Show InChI InChI=1S/C23H18ClNO3S/c1-29(27,28)20-12-10-16(11-13-20)21-15-25(19-9-5-8-18(24)14-19)23(26)22(21)17-6-3-2-4-7-17/h2-14H,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Barcelona Curated by ChEMBL					Assay Description Biochemical index for Prostaglandin G/H synthase 1 measured as, tromboxane 2 (TXB2) levels following blood coagulation				Bioorg Med Chem Lett 10: 1745-8 (2000) BindingDB Entry DOI: 10.7270/Q2ZG6RH7
					More data for this Ligand-Target Pair