BDBM50090634 3-(4-Fluoro-phenyl)-1-(2-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1,5-dihydro-pyrrol-2-one::CHEMBL300047

SMILES: CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)N(C1)c1ccccc1F)c1ccc(F)cc1

InChI Key: InChIKey=XIPWEBQITIJTCZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50090634 (3-(4-Fluoro-phenyl)-1-(2-fluoro-phenyl)-4-(4-metha...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)N(C1)c1ccccc1F)c1ccc(F)cc1 |t:11| Show InChI InChI=1S/C23H17F2NO3S/c1-30(28,29)18-12-8-15(9-13-18)19-14-26(21-5-3-2-4-20(21)25)23(27)22(19)16-6-10-17(24)11-7-16/h2-13H,14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
University of Barcelona Curated by ChEMBL					Assay Description Biochemical index for Prostaglandin G/H synthase 2 measured as, PGE-2 levels in lipopolysaccharide (LPS)-challenged human whole blood				Bioorg Med Chem Lett 10: 1745-8 (2000) BindingDB Entry DOI: 10.7270/Q2ZG6RH7
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50090634 (3-(4-Fluoro-phenyl)-1-(2-fluoro-phenyl)-4-(4-metha...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)N(C1)c1ccccc1F)c1ccc(F)cc1 |t:11| Show InChI InChI=1S/C23H17F2NO3S/c1-30(28,29)18-12-8-15(9-13-18)19-14-26(21-5-3-2-4-20(21)25)23(27)22(19)16-6-10-17(24)11-7-16/h2-13H,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Barcelona Curated by ChEMBL					Assay Description Biochemical index for Prostaglandin G/H synthase 1 measured as, tromboxane 2 (TXB2) levels following blood coagulation				Bioorg Med Chem Lett 10: 1745-8 (2000) BindingDB Entry DOI: 10.7270/Q2ZG6RH7
					More data for this Ligand-Target Pair