BDBM50090726 1-(2-{2-[2-(2-Acetylamino-3-naphthalen-2-yl-propionylamino)-3-(4-chloro-phenyl)-propionylamino]-3-pyridin-2-yl-propionylamino}-propionyl)-pyrrolidine-2-carboxylic acid (1-carbamoyl-ethyl)-amide::CHEMBL264526

SMILES: C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H](Cc1ccccn1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(C)=O)C(N)=O

InChI Key: InChIKey=JDLOJJXTADSJAR-DJPDSMPUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50090726 (1-(2-{2-[2-(2-Acetylamino-3-naphthalen-2-yl-propio...) Show SMILES C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H](Cc1ccccn1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(C)=O)C(N)=O Show InChI InChI=1S/C43H49ClN8O7/c1-25(38(45)54)47-42(58)37-12-8-20-52(37)43(59)26(2)48-39(55)36(24-33-11-6-7-19-46-33)51-41(57)35(22-28-14-17-32(44)18-15-28)50-40(56)34(49-27(3)53)23-29-13-16-30-9-4-5-10-31(30)21-29/h4-7,9-11,13-19,21,25-26,34-37H,8,12,20,22-24H2,1-3H3,(H2,45,54)(H,47,58)(H,48,55)(H,49,53)(H,50,56)(H,51,57)/t25-,26-,34-,35+,36+,37+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Concentration of the peptide which displaces 50% of 125 I-[D-Lys6] gonadotropin-releasing hormone bound to rat pituitary membranes				J Med Chem 43: 2831-6 (2000) BindingDB Entry DOI: 10.7270/Q29P30W3
					More data for this Ligand-Target Pair