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BDBM50090762 (R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxylic acid methyl ester::CHEMBL97857

SMILES: CCCN(C(C)C)C1COc2cccc(C(=O)OC)c2C1

InChI Key: InChIKey=FQVJYXWHSJKBKK-UHFFFAOYSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090762   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50090762
PNG
((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Show SMILES CCCN(C(C)C)C1COc2cccc(C(=O)OC)c2C1
Show InChI InChI=1S/C17H25NO3/c1-5-9-18(12(2)3)13-10-15-14(17(19)20-4)7-6-8-16(15)21-11-13/h6-8,12-13H,5,9-11H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

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PC sid
UniChem

Patents

Similars
PubMed
 0.320n/an/an/an/an/an/an/an/a



AstraZeneca R&D Södertälje

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...

J Med Chem 43: 2837-50 (2000)


BindingDB Entry DOI: 10.7270/Q2610ZJK
More data for this
Ligand-Target Pair