BDBM50090917 CHEMBL3581863

SMILES: OC[C@@H](O)Cn1c2-c3ccccc3C(=O)c2c2ccc(I)cc2c1=O

InChI Key: InChIKey=XVOSASZNKJDPED-NSHDSACASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50090917 (CHEMBL3581863) Show SMILES OC[C@@H](O)Cn1c2-c3ccccc3C(=O)c2c2ccc(I)cc2c1=O |r| Show InChI InChI=1S/C19H14INO4/c20-10-5-6-12-15(7-10)19(25)21(8-11(23)9-22)17-13-3-1-2-4-14(13)18(24)16(12)17/h1-7,11,22-23H,8-9H2/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human recombinant TPD2 activity using 5'phosphotyrosine-containing 19-mer single-stranded oligonucleotide DNA substrate by PAGE assay				J Med Chem 58: 3997-4015 (2015) Article DOI: 10.1021/acs.jmedchem.5b00303 BindingDB Entry DOI: 10.7270/Q2DN46S6
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 1 (TDP1) (Homo sapiens (Human))	BDBM50090917 (CHEMBL3581863) Show SMILES OC[C@@H](O)Cn1c2-c3ccccc3C(=O)c2c2ccc(I)cc2c1=O |r| Show InChI InChI=1S/C19H14INO4/c20-10-5-6-12-15(7-10)19(25)21(8-11(23)9-22)17-13-3-1-2-4-14(13)18(24)16(12)17/h1-7,11,22-23H,8-9H2/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of recombinant TPD1 (unknown origin) activity using 3'-phosphotyrosine-containing 5'-[32P]-labeled single-stranded DNA oligonucleotide by ...				J Med Chem 58: 3997-4015 (2015) Article DOI: 10.1021/acs.jmedchem.5b00303 BindingDB Entry DOI: 10.7270/Q2DN46S6
					More data for this Ligand-Target Pair