BDBM50090952 CHEMBL3582023
SMILES: CC(C)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)c1nnc(o1)C1CC1
InChI Key: InChIKey=SVNXFSNLYHVJLD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (MOUSE) | BDBM50090952 (CHEMBL3582023) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes | J Med Chem 58: 4266-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00283 BindingDB Entry DOI: 10.7270/Q2542QBG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50090952 (CHEMBL3582023) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes | J Med Chem 58: 4266-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00283 BindingDB Entry DOI: 10.7270/Q2542QBG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50090952 (CHEMBL3582023) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Activity at human CB1 receptor expressed in CHO cells assessed as cAMP accumulation incubated for 30 mins by time-resolved FRET assay | J Med Chem 58: 4266-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00283 BindingDB Entry DOI: 10.7270/Q2542QBG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50090952 (CHEMBL3582023) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Activity at human CB2 receptor expressed in CHO cells assessed as cAMP accumulation incubated for 30 mins by time-resolved FRET assay | J Med Chem 58: 4266-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00283 BindingDB Entry DOI: 10.7270/Q2542QBG | |||||||||||
More data for this Ligand-Target Pair |