BDBM50091357 CHEMBL3582301

SMILES: Fc1cc(ccc1C(=O)NC1CCCNC1)-c1cc(F)c2ncc(Cc3ccc4ncccc4c3)n2c1

InChI Key: InChIKey=GUMJWHJDIQZKDL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50091357 (CHEMBL3582301) Show SMILES Fc1cc(ccc1C(=O)NC1CCCNC1)-c1cc(F)c2ncc(Cc3ccc4ncccc4c3)n2c1 Show InChI InChI=1S/C29H25F2N5O/c30-25-13-19(6-7-24(25)29(37)35-22-4-2-9-32-15-22)21-14-26(31)28-34-16-23(36(28)17-21)12-18-5-8-27-20(11-18)3-1-10-33-27/h1,3,5-8,10-11,13-14,16-17,22,32H,2,4,9,12,15H2,(H,35,37)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of C-Met (unknown origin) using polu (Glu,Tyr)4:1 substrate after 30 mins incubation by multi-well spectrophotometry				ACS Med Chem Lett 6: 507-12 (2015) Article DOI: 10.1021/ml5004876 BindingDB Entry DOI: 10.7270/Q2QV3P79
					More data for this Ligand-Target Pair