BDBM50091363 CHEMBL3582295

SMILES: Fc1cc(ccc1C(=O)N1CCC2(COC2)C1)-c1cc(F)c2ncc(Cc3ccc4ncccc4c3)n2c1

InChI Key: InChIKey=NBOGKZQHDLWCQH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50091363 (CHEMBL3582295) Show SMILES Fc1cc(ccc1C(=O)N1CCC2(COC2)C1)-c1cc(F)c2ncc(Cc3ccc4ncccc4c3)n2c1 Show InChI InChI=1S/C30H24F2N4O2/c31-25-12-20(4-5-24(25)29(37)35-9-7-30(16-35)17-38-18-30)22-13-26(32)28-34-14-23(36(28)15-22)11-19-3-6-27-21(10-19)2-1-8-33-27/h1-6,8,10,12-15H,7,9,11,16-18H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of C-Met (unknown origin) using polu (Glu,Tyr)4:1 substrate after 30 mins incubation by multi-well spectrophotometry				ACS Med Chem Lett 6: 507-12 (2015) Article DOI: 10.1021/ml5004876 BindingDB Entry DOI: 10.7270/Q2QV3P79
					More data for this Ligand-Target Pair