BDBM50091368 CHEMBL3582290

SMILES: CNC(=O)c1cccc(c1)-c1cc(F)c2ncc(Cc3ccc4ncccc4c3)n2c1

InChI Key: InChIKey=QZJRILHHQOUNIE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50091368 (CHEMBL3582290) Show SMILES CNC(=O)c1cccc(c1)-c1cc(F)c2ncc(Cc3ccc4ncccc4c3)n2c1 Show InChI InChI=1S/C25H19FN4O/c1-27-25(31)19-5-2-4-17(12-19)20-13-22(26)24-29-14-21(30(24)15-20)11-16-7-8-23-18(10-16)6-3-9-28-23/h2-10,12-15H,11H2,1H3,(H,27,31)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of C-Met (unknown origin) using polu (Glu,Tyr)4:1 substrate after 30 mins incubation by multi-well spectrophotometry				ACS Med Chem Lett 6: 507-12 (2015) Article DOI: 10.1021/ml5004876 BindingDB Entry DOI: 10.7270/Q2QV3P79
					More data for this Ligand-Target Pair