BDBM50091447 (E)-3-(4-tert-Butyl-phenyl)-N-{5-[4-(1H-indol-3-yl)-piperidin-1-yl]-pentyl}-acrylamide::CHEMBL53130::TCMDC-139247

SMILES: CC(C)(C)c1ccc(\C=C\C(=O)NCCCCCN2CCC(CC2)c2c[nH]c3ccccc23)cc1

InChI Key: InChIKey=CBXCPBKAXMHRQS-DTQAZKPQSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091447 ((E)-3-(4-tert-Butyl-phenyl)-N-{5-[4-(1H-indol-3-yl...) Show SMILES CC(C)(C)c1ccc(\C=C\C(=O)NCCCCCN2CCC(CC2)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C31H41N3O/c1-31(2,3)26-14-11-24(12-15-26)13-16-30(35)32-19-7-4-8-20-34-21-17-25(18-22-34)28-23-33-29-10-6-5-9-27(28)29/h5-6,9-16,23,25,33H,4,7-8,17-22H2,1-3H3,(H,32,35)/b16-13+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against C-C chemokine receptor type 2				Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z
					More data for this Ligand-Target Pair