BDBM50091683 CHEMBL438096::N-alpha-Ac-[Trp24]PYY(22-36)-NH2(N-alpha-Ac-ASWAHYLNLVTRQRY-NH2)
SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
InChI Key: InChIKey=VTCHWWWSQIHVEE-HFSMTEEUSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NPY2R (RAT) | BDBM50091683 (CHEMBL438096 | N-alpha-Ac-[Trp24]PYY(22-36)-NH2(N-...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cincinnati Medical Center Curated by ChEMBL | Assay Description Tested for the affinity for intestinal PYY from rat jejunum by using short circuit current (SCC) method. | J Med Chem 43: 3420-7 (2000) BindingDB Entry DOI: 10.7270/Q2QR4WCX | |||||||||||
More data for this Ligand-Target Pair |