BDBM50091883 (S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-4-methylsulfanyl-butyrylamino)-cyclopentanecarbonyl]-amino}-propionic acid::CHEMBL61410
SMILES: CSCC[C@H](S)C(=O)NC1(CCCC1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(O)=O
InChI Key: InChIKey=VBTCEOFCVYGVOQ-VXKWHMMOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human)) | BDBM50091883 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-4-methyl...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair |