BDBM50092010 CHEMBL3582385

SMILES: Fc1ccc(cc1)S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc3[nH]ncc3c2)c1F

InChI Key: InChIKey=OVZUWMSLWUONJX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50092010 (CHEMBL3582385) Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc3[nH]ncc3c2)c1F Show InChI InChI=1S/C20H11F3N4O2S/c21-14-2-4-15(5-3-14)30(28,29)27-18-8-7-17(22)16(19(18)23)6-1-12-9-13-11-25-26-20(13)24-10-12/h2-5,7-11,27H,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	917	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair