BDBM50092037 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-methyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL63209

SMILES: CN1c2ccccc2CCC(N2CCN(Cc3ccc(Cl)cc3)CC2)C1=O

InChI Key: InChIKey=QJZDCDLDKXELAM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50092037 (3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-methyl-1,...) Show SMILES CN1c2ccccc2CCC(N2CCN(Cc3ccc(Cl)cc3)CC2)C1=O Show InChI InChI=1S/C22H26ClN3O/c1-24-20-5-3-2-4-18(20)8-11-21(22(24)27)26-14-12-25(13-15-26)16-17-6-9-19(23)10-7-17/h2-7,9-10,21H,8,11-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity at human Dopamine receptor D4 by [3H]- YM 09151 displacement.				Bioorg Med Chem Lett 10: 2119-22 (2000) BindingDB Entry DOI: 10.7270/Q2SN0869
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50092037 (3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-methyl-1,...) Show SMILES CN1c2ccccc2CCC(N2CCN(Cc3ccc(Cl)cc3)CC2)C1=O Show InChI InChI=1S/C22H26ClN3O/c1-24-20-5-3-2-4-18(20)8-11-21(22(24)27)26-14-12-25(13-15-26)16-17-6-9-19(23)10-7-17/h2-7,9-10,21H,8,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity at human Dopamine receptor D2 by [3H]- YM 09151 displacement.				Bioorg Med Chem Lett 10: 2119-22 (2000) BindingDB Entry DOI: 10.7270/Q2SN0869
					More data for this Ligand-Target Pair