BDBM50092048 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1,3-dimethyl-1,3-dihydro-indol-2-one::CHEMBL67429

SMILES: CN1C(=O)C(C)(N2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12

InChI Key: InChIKey=KRYKJSKXDBEMED-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50092048 (3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1,3-dimethy...) Show SMILES CN1C(=O)C(C)(N2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C21H24ClN3O/c1-21(18-5-3-4-6-19(18)23(2)20(21)26)25-13-11-24(12-14-25)15-16-7-9-17(22)10-8-16/h3-10H,11-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity at human Dopamine receptor D2 by [3H]- YM 09151 displacement.				Bioorg Med Chem Lett 10: 2119-22 (2000) BindingDB Entry DOI: 10.7270/Q2SN0869
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50092048 (3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1,3-dimethy...) Show SMILES CN1C(=O)C(C)(N2CCN(Cc3ccc(Cl)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C21H24ClN3O/c1-21(18-5-3-4-6-19(18)23(2)20(21)26)25-13-11-24(12-14-25)15-16-7-9-17(22)10-8-16/h3-10H,11-15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity at human Dopamine receptor D4 by [3H]- YM 09151 displacement.				Bioorg Med Chem Lett 10: 2119-22 (2000) BindingDB Entry DOI: 10.7270/Q2SN0869
					More data for this Ligand-Target Pair