BDBM50092125 CHEMBL37300::{4-[4-(4-Carbamimidoyl-phenyl)-piperazin-1-yl]-phenoxy}-acetic acid

SMILES: NC(=N)c1ccc(cc1)N1CCN(CC1)c1ccc(OCC(O)=O)cc1

InChI Key: InChIKey=AETCMTSWTLGAFY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50092125 (CHEMBL37300 | {4-[4-(4-Carbamimidoyl-phenyl)-piper...) Show SMILES NC(=N)c1ccc(cc1)N1CCN(CC1)c1ccc(OCC(O)=O)cc1 Show InChI InChI=1S/C19H22N4O3/c20-19(21)14-1-3-15(4-2-14)22-9-11-23(12-10-22)16-5-7-17(8-6-16)26-13-18(24)25/h1-8H,9-13H2,(H3,20,21)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Inhibition of fibrinogen binding to platelet glycoprotein alpha IIb beta-3 integrin in ELISA				Bioorg Med Chem Lett 8: 1531-6 (1998) BindingDB Entry DOI: 10.7270/Q21838P3
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50092125 (CHEMBL37300 | {4-[4-(4-Carbamimidoyl-phenyl)-piper...) Show SMILES NC(=N)c1ccc(cc1)N1CCN(CC1)c1ccc(OCC(O)=O)cc1 Show InChI InChI=1S/C19H22N4O3/c20-19(21)14-1-3-15(4-2-14)22-9-11-23(12-10-22)16-5-7-17(8-6-16)26-13-18(24)25/h1-8H,9-13H2,(H3,20,21)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of glycoprotein IIb/III and platelet aggregation in human platelet rich plasma				J Med Chem 43: 3453-73 (2000) BindingDB Entry DOI: 10.7270/Q2ZS2X79
					More data for this Ligand-Target Pair