BDBM50092296 1-(Naphthalene-2-sulfonyl)-piperidine-4-carboxylic acid (1-benzyl-2-ethylcarbamoyl-2-oxo-ethyl)-amide::CHEMBL68874

SMILES: CCNC(=O)C(=O)C(Cc1ccccc1)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=JVFVDIBUGJFPNY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50092296 (1-(Naphthalene-2-sulfonyl)-piperidine-4-carboxylic...) Show SMILES CCNC(=O)C(=O)C(Cc1ccccc1)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C28H31N3O5S/c1-2-29-28(34)26(32)25(18-20-8-4-3-5-9-20)30-27(33)22-14-16-31(17-15-22)37(35,36)24-13-12-21-10-6-7-11-23(21)19-24/h3-13,19,22,25H,2,14-18H2,1H3,(H,29,34)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
KNOLL AG Curated by ChEMBL					Assay Description Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytes				Bioorg Med Chem Lett 10: 2187-91 (2001) BindingDB Entry DOI: 10.7270/Q28K78BD
					More data for this Ligand-Target Pair