BDBM50092299 1-(Quinoline-3-carbonyl)-piperidine-4-carboxylic acid (1-benzyl-2-carbamoyl-2-oxo-ethyl)-amide::CHEMBL304400

SMILES: NC(=O)C(=O)C(Cc1ccccc1)NC(=O)C1CCN(CC1)C(=O)c1cnc2ccccc2c1

InChI Key: InChIKey=DWIRLLLWIBKLNA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50092299 (1-(Quinoline-3-carbonyl)-piperidine-4-carboxylic a...) Show SMILES NC(=O)C(=O)C(Cc1ccccc1)NC(=O)C1CCN(CC1)C(=O)c1cnc2ccccc2c1 Show InChI InChI=1S/C26H26N4O4/c27-24(32)23(31)22(14-17-6-2-1-3-7-17)29-25(33)18-10-12-30(13-11-18)26(34)20-15-19-8-4-5-9-21(19)28-16-20/h1-9,15-16,18,22H,10-14H2,(H2,27,32)(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
KNOLL AG Curated by ChEMBL					Assay Description Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytes				Bioorg Med Chem Lett 10: 2187-91 (2001) BindingDB Entry DOI: 10.7270/Q28K78BD
					More data for this Ligand-Target Pair