BDBM50092303 1-[(E)-(3-Phenyl-acryloyl)]-piperidine-4-carboxylic acid (1-aminooxalyl-3-methyl-butyl)-amide::CHEMBL303024

SMILES: CC(C)CC(NC(=O)C1CCN(CC1)C(=O)C=Cc1ccccc1)C(=O)C(N)=O

InChI Key: InChIKey=IECBICSWLZZLJC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50092303 (1-[(E)-(3-Phenyl-acryloyl)]-piperidine-4-carboxyli...) Show SMILES CC(C)CC(NC(=O)C1CCN(CC1)C(=O)C=Cc1ccccc1)C(=O)C(N)=O |w:17.18| Show InChI InChI=1S/C22H29N3O4/c1-15(2)14-18(20(27)21(23)28)24-22(29)17-10-12-25(13-11-17)19(26)9-8-16-6-4-3-5-7-16/h3-9,15,17-18H,10-14H2,1-2H3,(H2,23,28)(H,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
KNOLL AG Curated by ChEMBL					Assay Description Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytes				Bioorg Med Chem Lett 10: 2187-91 (2001) BindingDB Entry DOI: 10.7270/Q28K78BD
					More data for this Ligand-Target Pair